The basic aim of scientific research of this doctoral thesis is to study the role of health and social management in the organization of public health and social systems at the regional and subregional level of self-government. Health system is dynamic system which needs to be rationally managed and coordinated in order to ensure health care availability for all citizens living in the area. The basis of the health care system at the regional level consists of a primary health care network for which the organization is responsible by Counties. Counties have ,through the legal framework of the authorization, power to manage the system of primary health care, through the founding rights of institutions in the health care also County took over responsibility for the operation of health facilities by the administrative council. County management and management of health are coordinating the work of the health care system , which the task of health care is to be available to all citizens. Interviewing doctors, administration of health centers and representatives of the regional government has been used as a method for achieving this task. The results indicate the importance of strengthening management in the organization of the health system at the County level organizations. The health system, the part relating to primary health care, is necessary to be decentralized, health centers, with its management, along with local and county government should assume the liability for the organization of health care which also must accompany with financial decentralization.