Today, entrepreneurship represents not only a generator of national economy, but social development too. Therefore, we are currently in very challenging time, and entrepreneurship has increasing importance day by day, since it is very attractive branch of the economy. Croatian structure of small and medium enterprises is very similar to the European Union, in which more than 98% of entrepreneurial activity is made by SMEs. There are several existing problems in Croatian economy when it comes to the development of entrepreneurship. Definitely, we have a lack of additional investment in research and development, entrepreneurs education and innovation support. Entrepreneurial infrastructure and entrepreneurial support institutions play a key role in improving the current situation. Their development is the responsibility of regional and local self-government bodies. However, the highest state institution in Croatia which performs and supervises activities related to entrepreneurship is the Ministry of Economy, Entrepreneurship and Crafts. This graduate paper will also explain the strategies of other institutions and their ways of supporting entrepreneurs. Entrepreneurial infrastructure in Croatia is well developed and diversified, but the main problem is the excessive territorial centralization around the City of Zagreb. Therefore, it would be necessary to develop the existing support system, as well as the spatially distribute the centers of support. As an example of entrepreneurial institutions support to SMEs, I put the Company Torzo ltd, which has shown to be successful in using support funds in business improvement for several years.