This doctoral dissertation was written as a guideline for achieving a basic goal of presenting new solutions and answers to questions of managing Istria as a tourist destination. Having observed an increasing need for a more efficient tourism management, based on a balanced development and the use of potentials i.e. resources, this dissertation explores actual assertions and possibilities of new perspectives. Tourism destination management is a complex challenge requiring a multidisciplinary and interdisciplinary approach, synergy and coordination of all tourism entities, leading to the same result. This dissertation provides detailed information on the existing management style as well as findings resulting from the multi-month long field work based on the future of managing Istria as a tourist destination. Furthermore, based on obtained research results, methods of tourism destination quality management have been offered. If tourism destination management is organized and synergistically conducted under agreed guidelines, more quality tourism results in line with those achieved by top destinations in our competitive regions can be expected. Though the Istrian region has been recognized as a quality tourist destination for years, its possibility for a bigger and better step forward must be pointed out in terms of managing the destination itself. To achieve optimal solutions, professional management modules and innovative guidelines set by world tourism trends must be followed in order to adjust them to our needs and requirements. A certain reorganization of some management branches as well as permanent staff education is essential for tourism in Istria and Croatia as a whole. As this doctoral dissertation has been focused on the issue of management as the basis for the very process of tourism destination development, it has been necessary to obtain opinions, experiences and suggestion from local tourism institutions and players to reach correct solutions based on obtained research information. The existing condition of Istrian tourism management as well as the condition of the destination itself is certainly not unsatisfactory. However, available resources and rather broad experience in tourism should contribute to the increased quality of the Istrian region as a tourist destination. Tourism ia an industry that involves networks or organisations working together. This is particulary true in regional areas, where the dependence on successful tourism marketing and management by local communities, business and common sinergy (Cooper, Scott, March, Wilkinson, Pforr, Thompson, 2006.).