Entrepreneurship is a collection of creative activities where enterprising individual combines land, labor, and capital to run his entrepreneurial venture. An entrepreneur is an individual whose name in Croatian society is often associated with negative associations, but it is more about the context of the environment. It is obvious that in some different areas, such as Western Europe, entrepreneurship and entrepreneur are associated with something positive and good such as, entrepreneurial skills that can be used to improve business or personal life. This paper will be clarifying entrepreneurial skills: personal, interpersonal and group skills. Definition, combining and managing entrepreneurial skills with purpose to improve organization’s performance. Although entrepreneurship is often associated with terms: profit, success, a private business organization, innovation, in this paper, it will be related to the non-profit organizations and address the question of how entrepreneurial skills are relevant to the operation and the work of non-profit organizations. Following the definition of non-profit organizations, and by clarifying their operation, a focus will be on non-profit organizations in Croatia since their appearance until today. At the same time, this paper will discuss the development of the non-profit organizations on the example of the United Kingdom. From each country, there will be one non-profit organization used as an example of a successful non-profit.